I probably should have done a little more research to determine if there are any new or better offerings than the ones we used when building our wedding website, but there have been complaints thus far.
GoDaddy provides one of the lowest cost domain registration services at around $10/year. I decided to snap up vihho.net in addition to vihho.com, to prevent domain squatting.
For website hosting, discount ASP.net supports the latest and greatest Microsoft technologies: ASP.NET 3.5, LINQ, AJAX, SQL Server 2005. I've also heard good things from Ryan about ORCS Web, which has hosted some Microsoft sites and partners with many of his ASP Insider buddies.